A/Prof Siskind trained as a psychiatrist in Australia and the United States.    He works clinically as a psychiatrist at Metro South Addiction and Mental Health Service with people with treatment refractory schizophrenia. His research interests include clozapine, treatment refractory schizophrenia and the cardiometabolic comorbidities of schizophrenia. He was awarded an NHMRC Early Career Fellowship (2016-2019) looking at the cardio-metabolic health of people with severe and persistent mental illness.  He has over 90 peer reviewed publications, including 2 first author in the highly ranked British Journal of Psychiatry, and has over $4.5 million in research grants in the past 5 years.